Marty is a process chemist (by training) but has been working on documentation platforms and technologies for the past decade. He is part of a team that is focused on evolving a modern pharmaceutical development organization towards a structured data-first documentation paradigm, using a widely diverse set of tools from BIOVIA and others. He’s been using Pipeline Pilot, the focus of this presentation, since 2015, generally in the context of OneLab-based solutions.
Maryam ESHRAGHI EVARI is a Process Data Scientist at Regeneron, where she has been for the last four years. Her work is centered around process data pipelines and visualizations. Prior to this, she worked as a Neuro Image Data Scientist at the Child Mind Institute. Maryam earned her master’s degree in computer science from the New Jersey Institute of Technology. During her master’s program, her research was on scene understanding with the focus on deep Neural Networks and Bayesian networks.
After graduating with a BS degree in chemistry from the University of Kinshasa, DR Congo, I moved to the US with a pre-doctoral Fulbright Scholarship award. Then, I got a PhD in Biomedical Sciences from the Icahn School of medicine at Mount Sinai, working with Drs George Némethy, Shalom Rackovsky and Harold Scheraga (chemistry department, Cornell University), focusing on molecular mechanics force field development and applications to biomolecules. With a Donahue Foundation postdoctoral Fellowship award, I did a postdoc in the chemistry department at Wesleyan University, working with Dr. David Beveridge on molecular dynamics simulation of proteins and protein-nucleic acids interactions. I then moved to the biopharmaceutical industry, working successively as a computational chemist at BioNumerik Pharmaceutical, TX (4 years), Targacept Inc., NC (7 years), Proteostasis Therapeutics, Inc.,MA (4 years) and RCH Solutions, MA (2 years). I’m currently working as a Principal Scientist at Sanofi, MA, since 2020, using both physics-based and AI/ML methods in CADD. Additional information about my background and career can be found on my linkedin profile.
After graduating with a Masters in Biotechnology from Birmingham University in the UK, Tristan was for many years a lab bench antibody discovery scientist at Genzyme before advocating that his data handling endeavours on behalf of the group deserved a full-time role when he relocated to the US in 2012 after the acquisition by Sanofi. Now he leads the US arm of the LMR Digital Biologics group. Tristan and Angela are part of the Digital Biologics group within Sanofi’s Large Molecule Research organization. The DBxP group is responsible for all things “data” which encompasses building the data governance policies; maintaining and developing the primary foundation systems and cultivating the data-first culture established in Sanofi R&D. Part of that mandate includes developing tools to support scientists with their workflows involving data capture; processing; reporting and interrogation and Biovia Pipeline Pilot is used extensively in those efforts.
Chris LOWDEN holds a Ph.D. in Medicinal Chemistry from UNC Chapel Hill. He worked as a medicinal chemist for over a decade before moving into the Software industry in the mid 2000s. He founded Workflow Informatics Corp in December 2013. Workflow Informatics provides world-class research informatics consulting services.
Dr. Ahmed is the President and CSO of VITRUVIAE, a privately held biotechnology company developing therapeutics and vaccines for cancer, infectious diseases, and mental illnesses. He was formerly the SVP and CSO of Y-mAbs Therapeutics, a commercial stage public biotechnology company, and a faculty member in the Department of Pediatrics at Memorial Sloan Kettering Cancer Center. Dr. Ahmed is an expert in antibody and protein engineering and has co-chaired the Engineering Bispecific Antibodies track at the PEGS Boston meeting for the past 7 years. He received his PhD in Biochemistry and Structural Biology from Stony Brook University, followed by post-doctoral training in cancer immunology at Memorial Sloan Kettering.
Laurent HOFFER, Ph.D. is a Research Scientist at the Drug Discovery department of the Ontario Institute for Cancer Research (OICR). His main focus has been the computer-aided development of molecular probes and potent inhibitors for diverse targets, including protein kinases, bromodomains and WDR-domain containing proteins. Dr. Hoffer received his Ph.D. in chemoinformatics from the University of Strasbourg (Pr Varnek Lab) in 2013. During his doctoral research, he specialized in the molecular docking of small organic compounds and their optimization through in silico methods. He pursued his post-doctoral fellowship at the Cancer Research Centre of Marseille (CRCM, France) in the Morelli team, where he developed the molecular modeling methods (DOTS & CovaDOTS) for the structure-guided optimization of compounds. Finaly, he also contributed to the development of the ChemoDOTS web-server (https://chemodots.marseille.inserm.fr).
Olexandr ISAYEV is an Associate Professor at the Department of Chemistry at Carnegie Mellon University. In 2008, Olexandr received his Ph.D. in computational chemistry. He was a Postdoctoral Research Fellow at the Case Western Reserve University and a scientist at the government research lab. Before CMU, he was a faculty at UNC Eshelman School of Pharmacy, the University of North Carolina at Chapel Hill. Olexandr received the “Emerging Technology Award” from the American Chemical Society (ACS) and the GPU computing award from NVIDIA Corp. Olexandr is 2023 Scialog Fellow and Associate Editor for ACS Journal of Chemical Information and Modeling. The research in his lab focuses on connecting artificial intelligence (AI) with chemical sciences.
Dr. Md Jamil HOSSAIN is a Postdoctoral Research Associate at Brown University School of Engineering working under the supervision of Professor Yue Qi. Dr. Hossain obtained his B.S. and M.S. degrees in Mechanical Engineering from Bangladesh University of Engineering and Technology in 2012 and 2016, respectively. He obtained his Ph.D. degree in Mechanical Engineering from The Pennsylvania State University with research focused on the multiscale modeling of the electrode/electrolyte interface of lithium-ion batteries and solid oxide electrolysis cell. His PhD work as well as two internships at Idaho National Laboratory involved the development of ReaxFF and eReaxFF reactive molecular dynamics force fields. Currently, as a Postdoctoral Research Associate, using multiscale modeling, he works on designing and developing battery electrolytes targeting applications for high voltage, high and low temperature, and fast charging. Dr. Hossain loves to travel around the world and experience different culture and nature. He enjoys hiking in his spare time.
Adam LYONS is a Life Science Solutions Consultant supporting BIOVIA’s Enterprise clients. He holds a B.Sc. in Chemical Engineering from Northeastern University, and formerly worked at Regeneron in its Preclinical Manufacturing and Process Development department with a role in Technology Transfer & Logistics. He was a key facilitator of preclinical research studies gating emergency use authorization of Regeneron’s COVID-19 antibody cocktail. Currently, he leverages his knowledge of bioprocessing and controlled substances domains to demonstrate the value of BIOVIA’s lab informatics solutions, which encompass method execution, inventory management, visualizations and more!
Brian has more than 20 years of marketing and sales experience in the consumer packaged goods industry, with expertise in brand management and go-to-market strategy. For the last five years, he has led the global marketing for the consumer packaged goods and retail industry team, specializing in content strategy development and execution to address specific industry challenges facing brand manufacturers, packaging suppliers and retailers.
Bruce GRIESHABER transformed BIOVIA ONE Lab with the addition of Study Protocols enabling a variety of process development and quality control processes. Bruce’s responsibility on the Product Management team is for Sample Management and Task Planner. Prior to joining BIOVIA, Bruce was the Director of Corporate Quality Control at a large pharmaceutical company with responsibilities for global laboratory solutions and associated business processes.
Chris began his career as a molecular biologist, focusing on identifying and cloning novel cellular mobility and signaling proteins. The sequence analysis aspect of this work led him to program automated analysis pipelines, eventually transitioning into software product management.
Over the past 10 years at BIOVIA, Dassault Systèmes, Chris has worked as a Professional Services Project Manager, focusing on CPG companies, and as a Formulations Product Portfolio Director. Both roles center on identifying and delivering the best solutions for BIOVIA’s customers. A Massachusetts native, Chris is a lifelong Boston sports fan.
Clement is an Aerospace Engineer with 10 years of experience, having worked in France, Germany, and the US. Specializing in aerospace engineering, cloud computing, and data science, he has collaborated with industry leaders such as Dassault Systèmes, NASA, and Airbus. Now a Product Manager at Dassault Systèmes, Clement oversees the development of cloud-based Machine Learning applications and Pipeline Pilot. He is driven by a passion for health and science topics.
Scientist and software developer with 30+ years’ experience. Current focus on data science, machine learning, and optimization applied to problems in drug discovery, materials, and formulations. Specific interests in model validation, model domain of applicability measures, uncertainty assessment in model predictions, non-gradient-based multi-objective optimization strategies, and active learning approaches to experimental design, model refinement, and optimization.
Expertise: Biotherapeutics, Small Molecule Drug Discovery, Application of AI/ML
Bio: Dr. Deepa PANDIT from the Contract Research and Scientific Consulting team is Global Head of Life Sciences - Discovery Research at Dassault BIOVIA. She has over 10 years of biotech industry experience and is passionate about solving research issues of the Life Sciences Discovery field. She has deep technical expertise in the field of computational protein design and engineering including antibody-based biologics. She believes that appropriate computational methods reduce experimental burden. Before joining Dassault BIOVIA, she served as a Senior Group Leader, Antigen Design and Protein Expression at Cell Signaling Technology in Massachusetts.
Expertise: Lab Informatics, ELN, LES, LIMS, Instrumentation and Data Acquisition, Data Analytics
Bio: At BIOVIA Gene is providing the vision, strategy and management of the Laboratory Management product portfolio that includes the Electronic Laboratory Notebook, Laboratory Information Management System and the Laboratory Execution system.
Gene has over 30 years of experience in the Life Science industry developing and delivering Laboratory informatics solutions for the research, development and quality control labs.
Prior to joining BIOVIA, Gene led product development efforts for Zymark Corporation and REMP USA.
Gene obtained is BS in Mechanical Engineering from the University of Massachusetts in 1991.
Expertise: Quality Assurance, Quality Control, Quality Document Management, Quality Process Management, ONE Lab, LIMS, Structured Document Management
Bio: Jessica THEISEN is an Industry Process Consultant in North America at BIOVIA, a Dassault Systèmes brand. She has been with the company for 2 years and she has a Master’s degree in chemistry. Her background is in Pharmaceuticals specializing in Quality Control, Quality Assurance, Stability, and LIMS. Jessica’s role is to provide scientific and technical support for Dassault Systèmes’ customers in adopting our solutions for Document Management, Quality Process Management, and Laboratory Informatics across a range of industries.
John MCCARTHY has worked with leading companies to deliver software-based solutions to increase the pace of innovation for the past 30 years. An accomplished business strategist, he works with clients to understand their scientific, engineering as well as business challenges and identifying solutions for these challenges.
Expertise: Digital transformation, Materials Science and Formulation, Drug Discovery, Sustainability, Lab informatics
Bio: Dr. Kai ZHANG is the marketing director at BIOVIA, Dassault Systèmes. Dr. Zhang has over 15 year experience in global marketing, R&D and product development. He is a passionate advocate for empowering scientists to innovate better and faster with advanced software solutions. Dr. Zhang holds a Ph.D. in Organic Chemistry from University of Pittsburgh and an MBA from Carnegie Mellon University.
Kanishka DESAI is an Industry Process Consultant at Dassault Systèmes BIOVIA. He holds a BS degree in Chemical Engineering and an MS degree in Bioinformatics. He has previously worked in the agriculture tech and biotech industries. He has been with BIOVIA for five years, providing support in the use of applications for research and development, materials inventory, and laboratory informatics for companies in the chemicals, high-tech, oil & gas, consumer packaged goods, and biotech industries.
Expertise: Computational Biophysics and Chemistry
Bio: Kevin CASSIDY, Ph.D., Biosciences Application Scientist at BIOVIA, obtained his doctorate with a focus on computational biophysics and chemistry at the University of Pittsburgh. A member of the Berman and Durrant labs, he focused on combining the advantages of both in silico and in vitro experiments to study the RNA binding protein LARP1. He interfaced between wet and dry labs to design the most effective and efficient experiments that leveraged the strengths of both disciplines. As a pre-sales scientist at BIOVIA, he has contributed to validation studies focusing on small molecule optimization. He supports the BIOVIA Biosciences solutions that have functionality for biologics and/or small molecule design/discovery, such as Discovery Studio and Generative Therapeutics Design.
Expertise: Quality, Regulatory and Product Lifecycle in Biopharma and Med Device
Bio: Kevin is the VP of R&D for Quality & Regulatory solutions in DASSAULT SYSTEMES. As founder and former CEO of QUMAS Kevin has deep industry expertise across the Quality and Regulatory domains.
Expertise: Lab Informatics, ELN, LIMS, Digitalization
Bio: Kirsten GESENBERG is portfolio director for BIOVIA ONE Lab products. She began her career as a small molecule process chemist in the pharmaceutical industry. Since joining BIOVIA more than 15 years ago, she has been involved in the successful implementation of BIOVIA ONE Lab and Workbook across the Life Sciences industry.
I am R&D Development Director for Quality & Regulatory Apps on 3DX Platform. I have 23+ years of experience and has been with DASSAULT SYSTEMES for 13 years, managing the development of Quality & Regulatory apps targeted for multiple industries in Life Science Medical Devices, BioPharma, A&D, CPG, Energy, T&M etc.
As Discoverant’s Product Manager, Larry is part of the Product management organization within BIOVIA and is responsible for product development for the BIOVIA Discoverant solution. Larry obtained his Ph.D. from Virginia Tech under the direction of Professor John R. MORRIS, working on ultrahigh vacuum studies of the reaction mechanisms of ozone with saturated and unsaturated self-assembled monolayers. Prior to graduate school, Larry’s industrial experience includes four years as a New Process and Development Chemist working on scale up of chemical processes from pilot plant to full scale manufacturing.
Expertise: Scientific Informatics (Cheminformatics, Data Science), ELN, Search, Registration
Bio: Matthew SAGE, Ph.D. is a Senior Product Manager for Scientific Informatics at BIOVIA / Dassault Systèmes and received his Ph.D. in Organic Chemistry with Molecular Modelling from the University of Bath, UK.
Over the last 20 years he has helped customers from many industries to implement decision support tools that enable them to manage their specific scientific data requirements, ranging from small molecules to reactions and more recently chemically modified bimolecular entities. He also helped grow the Cheminformatics portfolio through various sales, support and services functions to become the industry standard it is today. Currently as a senior product manager, he manages the chemistry solutions at BIOVIA.
Mike WILSON is a product manager responsible for the BIOVIA Laboratory equipment, configuration management, and administration features. Mike focuses on the enterprise and integration capabilities of the laboratory services and has also worked with electronic laboratory notebook applications since joining BIOVIA in 2003. Prior to that, Mike led IT organizations in software and financial companies. His areas of expertise include support for regulated environments, business continuity planning, and best practices for deployment design/implementation.
Bioinformatician, Software Engineer, and Pipeline Pilot expert. Primary focus is utilizing Pipeline Pilot to solve data problems, parse/aggregate large amounts of data, streamline clinical data processing, create and utilize AI models, and generate dashboards for visualization/QC of data. Expert in data processing, image/video analysis, and AI model creation/usage.
Expertise: Materials Simulation, Laboratory informatics, and Data Science
Bio: Nick REYNOLDS is an Industry Process Consultant Director in North America at BIOVIA, a Dassault Systèmes, brand. He has been with the company for 30 years, and his background is in Materials Science, with a Ph.D. in Polymer Science and Engineering. Nick’s and his team’s role is in providing scientific and technical support for Dassault Systèmes’ customers in adopting our solutions for computational materials science, formulation management, laboratory informatics, and data science, across a range of industries.
Priya WESLEY is a Senior Product Manager in North America at BIOVIA, a Dassault Systèmes brand. She has been with the company for 14 years, with experience in solutioning for Formulation Management and Laboratory Informatics. Priya’s role is to provide a Scientific Search solution for synthetic chemistry, formulation management, and laboratory informatics across life sciences and CPG-R industries.
Expertise: Lab Informatics, ELN, LIMS, Digitalization
Bio: Stephen HAYWARD has a PhD in Chemical Engineering, with a background in laboratory informatics, chemical modeling, and environmental analysis. Originally from Toronto, Canada, he currently leads product marketing efforts for laboratory informatics solutions at BIOVIA in San Diego.
Subra NARAYANASAMY is a Senior Solutions Consultant at Dassault Systemes and specializes in Quality and Regulatory Compliance applications in BIOVIA suite of products.
Expertise: 3D Modeling and Simulation, computational chemistry, drug discovery
Bio: Tien LUU is the Product Manager and Principal Scientific Specialist at BIOVIA Dassault Systèmes, managing aspects of life science modeling and simulation predictive science solutions. She began her career as a Scientific Specialist after receiving her Ph.D. in Chemistry from the University of Wollongong, Australia. Since joining BIOVIA 22 years ago, Tien’s passion and excitement for helping customers accelerate their R&D have been steadfast and she is committed to improve customer experiences and product successes. In addition, she continues to be an active leader in scientific software product development, new program initiatives, and new applied and fundamental scientific research.
Ton VAN DAELEN is the Life Sciences Portfolio Lead at BIOVIA / Dassault Systèmes. He has helped pharmaceutical and biotech customers implement cloud solutions to address internal and external research collaboration challenges. Previously, Ton helped grow the Pipeline Pilot product in various support and product management functions and grow it into one of the premier research informatics frameworks in biopharma organizations. Today one of Ton’s interests is using this framework for building solutions that leverage AI and Machine Learning for the design of novel therapeutics. This helps pharma save significant cost in the discovery phase and get new drugs to market faster. Ton has a Ph.D. in theoretical chemistry from the University of Eindhoven, The Netherlands.
Graham JANSON has a background in Life Sciences as a Quality Control Chemist. He has spent the last 15 years both leading and implementing multi-discipline laboratory transformations with BIOVIA Professional Services.
He currently leads a specialized team with the mission of identifying and package repeatable solutions and best practices to accelerate the adoption and enhance the value of BIOVIA solutions.
Expertise: Materials modeling, data pipelining and lab informatics
Bio: Jason DeJONNAIS is an application scientist with 16 years in the BIOVIA brand. Prior to that he “earned” a PhD in chemical engineering from the University of Florida playing with toy polymer models on the computer.
Computational Biologist and Data Scientist with more than 15 years of experience in industry and academics. Areas of specialization include Bioinformatics, Machine learning, Statistics, molecular biology, and lab informatics.
Scientist with 10+ years’ experience on applying computational chemistry methods to aid drug discovery and materials development. Current focus is on investigation and application of new ML and AI-based methods to understand the complexities of bio-molecular interactions.
Brian RAKOWIECKI is responsible for Analytical Development Operations, BioTherapeutics Discovery, Product Development & Supply
Irfan Khan has a master’s degree in physics from Royal Holloway, University of London. Irfan is a Senior Applications Engineer on the hardware product team at Quantinuum.
He has worked for Quantinuum since 2018, previously holding positions with the scientific technical team and contributing to R&D and software development for chemistry-related projects.
Expertise: Drug Discovery, Biotherapeutics, Protein Engineering
Bio: Dr. VILLANUEVA completed a PhD in structural biology focusing on drugging protein-protein interactions with fragment derived small molecules. His postdoctoral studies centered around understanding the structure, function and pharmacology of G proteins and GPCRs. As a postdoc, Dr. Villanueva also played a pivotal role in the development of a therapeutic enzyme that has been out-licensed and is currently in phase II clinical trials. He then joined the pharmaceutical industry as a scientist, making contributions in the discovery and development of small molecules, PROTACs and therapeutic antibodies.
Floriane ESHAK graduated with a Bachelor's degree in Pharmacy from the German University in Cairo, Egypt in 2018. She then completed her Master’s degree in In Silico Drug Design atthe University of Paris, France in 2020. In 2021, she started her Ph.D. at the University Paris Cité, working on analyzing and developing nanobodies binding to metabotropic glutamate receptors using in silico tools under the supervision of Dr. Anne GOUPIL (Biovia, Dassault Systèmes), and Dr. Francine ACHER (University Paris Cité), and was funded by the National research agency. She obtained her PhD in 2023. Floriane then continued her research career as a postdoctoral researcher at the University Paris Cité and has recently joined Dassault Systèmes.
Gabriel is a Principal Research Associate in the Cell Culture Development group at Sanofi. His lab work primarily focuses on the development of High throughput cell culture models that scale to manufacturing scales. While doing so he discovered that legacy ways of working did not support large volumes of data. For the last 3 years he has served as the site transformation lead and product owner of digital cell culture workflows globally at Sanofi. He graduated from the University of Massachusetts at Dartmouth in 2020 with a bachelors in Bioengineering.
Angela, with a Master's in Data Science from Univ Maryland, joined the DBxP team in 2022 from her previous role supporting Bioprocess GMP activities at Novavax. Based in Maryland, she became LMR's first (and still only) fully remote employee. She quickly adopted the Pipeline Pilot platform and, in addition to the PLP-based tools she continually develops, brings her dashboarding expertise to the team. Angela and Tristan are part of the Digital Biologics group within Sanofi’s Large Molecule Research organization. The DBxP group is responsible for all things “data” which encompasses building the data governance policies; maintaining and developing the primary foundation systems and cultivating the data-first culture established in Sanofi R&D. Part of that mandate includes developing tools to support scientists with their workflows involving data capture; processing; reporting and interrogation and Biovia Pipeline Pilot is used extensively in those efforts.